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[慶賀]恭喜張清貿醫師升任北榮傳醫科主治醫師-20170201

作者 主題: [Tool] RepeatMasker  (閱讀 2385 次)

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« 回覆文章 #1 於: 二月 21, 2017, 11:50:18 pm »
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Transposable element

Transposable element (TE), also known as transposon or mobile element, is a diversity of DNA segments that can, in a process called transposition, move, or duplicate, from one location in the genome to another. The length of TEs ranges from less than 100-bp to more than 20-kb. After transposition, many types of TEs are flanked by short (~1–20 bp) direct repeats, target site duplications (TSDs), which are derived from the target sequence. However, some TE types, such as Helitron, several Harbinger families and CR1 retrotransposons, do not produce TSDs. The length of TSD is usually a characteristic of a group of TEs and its relatives, but may vary across different groups and superfamilies. TEs constitute the major part of repetitive sequences in most eukaryotic genomes. Other repetitive sequences include tandem repeats (satellite sequences or mini-satellite), sporadic genomic duplications and some multiple-copy host genes (such as rRNA, tRNA, histone genes, etc.). In fact, TEs can be viewed as intra-genomic parasitic elements. Similarly, inter-cellular virus can also be viewed as TEs since they can integrate into the host genome, such as the LTR-retrovirus. TEs have diverse evolutionary impact on host genome.
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